HAIR/MINERAL/TISSUE ANALYSIS

Hair analysis is a sophisticated laboratory technique used in preventive medicine for assessing mineral imbalances and metal toxicities in the human body. Utilizing these general diagnostic screening techniques, information regarding the following nutritional minerals and toxic metals can be assessed with greater accuracy than by any other diagnostic method.

Nutritional minerals tested: boron, calcium, chromium, cobalt, copper, germanium, iron, lithium, magnesium, manganese, molybdenum, nickel, phosphorus, potassium, selenium, silicon, sodium, strontium, tin, vanadium, zinc.

Toxic Metals tested: aluminum, antimony, arsenic, barium, beryllium, cadmium, lead, mercury, silver.

Toxic metal accumulations in the body such as aluminum, arsenic, cadmium, lead and mercury may interfere with proper vitamin and mineral utilization and can induce unfavorable metabolic consequences. For example, neurological and psychomotor dysfunction can be caused from chronic lead intoxication, aluminum overload, and mercury toxicity, hypertension from excessive cadmium stores, lead induced anemia and gout from excessive lead exposure. Toxic metals are a serious problem today contributing to many metabolic disorders and symptoms including fatigue, infections, high blood pressure, heart disease, cancer and diabetes. While routine blood tests cannot detect chronic heavy metal poisoning, hair analysis is one of the few methods approved by the Environmental Protection Agency for detecting toxic metals in the body. Hair analysis is the method of choice to analyze these elements in your body. It is simple and easy to do in your own home.

Upon completion of the test, Dr. Guberman will contact you for further explanation. There is no extra charge for this.

1 Test.....$95.00

MELATONIN BIORYTHYM AND CHALLENGE TEST(SALIVA)

Melatonin Biorythym & Challenge (MBC) test _________________________________________________________

Introduction

The Melatonin Biorhythm and Challenge (MBC) test requires four saliva specimens collected throughout a 24 hour cycle, followed by 2 challenges and 2 subsequent saliva collections. The functional integrity and therapeutic responses of the pineal gland are evaluated.

Information the test provides:

The test provides information on the dynamics and integrity of the melatonin biorhythm.

1. Baseline output reflecting the light suppressed state of the pineal and non-pineal melatonin production; e.g. intestinal tissue contribution.

2. Responsiveness of the pineal to reduced light or darkness, i.e. the functional integrity of the Retinal-Sympathetic-pineal-system.

3. The functioning of the internal clock that alternates melatonin output and controls the native circadian of melatonin release.

4. Two Post Challenge assessments

a. A melatonin challenge is given at a specified time before sleeping then a saliva sample is collected later on. This allows individualized assessment of dosing and timing of melatonin therapy.

b. In a second challenge, a melatonin precursor nutrient is employed at a specified time of day and subsequently a saliva sample is collected. This challenge evaluates the integrity of the melatonin synthesis pathway. The challenge doses are supplied.

Clinical Applications & Questions

A. Sleep & mood disorders B. Seasonal Depression C. Adjunct Cancer Therapy D. Immune Dysregulation E. BioRhythm disruptions F. Autonomic Dysrhythmias G. Low Body Temperature H. Thyroid Disease Is there a precursor deficit? Is there a production problem? Does your patient need Melatonin, and how much?

What to look for in Melatonin tests:

Melatonin values only confined to day and before sleep measurements, i.e. 18 hrs of the cycle, have minimal clinical relevance. Practically any day value is low while late night values show a variable increase depending on intensity of light exposure between sunset and sleep time. The MBC test offers clinically relevant data, evaluates a full 24 hr. melatonin cycle and also includes two challenge tests.

Basic Information

Melatonin is ubiquitous throughout the animal kingdom. In humans, melatonin obeys a diurnal circadian rhythm with the peak production being during the night hours (2:00 - 3:00 am). Melatonin is the molecular-level expression of darkness in biological organisms. The melatonin circadian therefore, provides the body with time-of-day and time-of-year biological signals. Being a lipophilic molecule, melatonin has access to all intracellular compartments.

I.Control and Release of Pineal Melatonin

In man, melatonin is produced by the pineal gland, a unique neuroendocrine transducer. Melatonin is synthesized from serotonin under conditions of darkness. The half life of melatonin in humans is about 48 minutes with most of it being catabolized in the liver into 6-sulfoxymelatonin which is cleared by the kidneys.

The increase in melatonin during the night tracks the duration of darkness. The final pineal innervation that leads to release of melatonin mediated by b-Adrenergic receptor The sympathetic control of melatonin is hindered by the use of b-Blockers. More subtle energies of fluctuating electro-magnetic fields demonstrate an inhibitory effect on melatonin output.

II. Biologic Roles of Melatonin

Melatonin exerts several biological influences.

A. Antioxidant Capacity: Melatonin is an in vitro & in vivo hydroxyl free radical scavenger. It exhibits remarkable antioxidant activity in doses of 0.2 - 0.4 mg/kg of body weight. Melatonin has a distinct DNA protective role and has a tendency to concentrate in the nucleus over the cytosol.

B. Immune Modulation: Melatonin is an immunomodulatory compound enhancing antigen activation of T-cells as well as increasing IgG and IgM output. As such, it may be an integral component in neuroimmunomodulation.

C. Hormone Modulation: Melatonin seems to exert a stimulatory effect on prolactin. As little as 6 mg of exogenous melatonin significantly stimulates prolactin output regardless of the time of day. The normal nocturnal prolactin surge may in part be under melatonin control. Melatonin is a potent antigonadal hormone which can synergise the effect of progestins to inhibit ovulation by a possible combination of direct effects on the ovary (i.e. follicle) and LH suppression at the pituitary level. Melatonin seems to influence glycemic control. Animal research has shown that insulin response to carbohydrate intake is depressed following the increase in melatonin levels. Furthermore, exogenous melatonin can inhibit growth hormone with a subsequent drop in blood glucose levels.

III. Melatonin and Age Correlations

Melatonin output is non-existent in the first 3-5 months of human life. A robust rhythm develops rapidly but then shows a drop during the years of sexual maturity after which, nocturnal output assumes an adult pattern. With advancing age, the melatonin biorhythm weakens showing less nocturnal output. This deterioration seems due to a reduction in the number of Beta-Adrenergic receptor sites on the pineal. The gland also shows an age related increase in calcification, but no demonstrable effect is ascribed to the concretions formed. The clinical consequences of age associated melatonin reduction are at present speculative and therefore rather controversial.

IV. Clinical and Pharmacological Use

A. Sleep Promotion Nightly Melatonin augmentation to physiologic or supraphysiologic range acts as a sleep induction agent and may reduce day time sleepiness. Research in delayed sleep phase syndrome has shown that 5 mg of melatonin given nightly for 28 days caused a sleep and wake time phase advance.Participants felt refreshed upon waking. It is not advisable to use melatonin during the day, or to overuse it, because melatonin has been shown to account for 40% of the drop in core-body temperature usually observed during night sleep. The use of b-Blockers can inhibit nocturnal melatonin output which may account in part for the sleep-disturbance side effects of b-Block

Many other tests only make evaluations from an 18hr cycle. DTI offers more clinically relevant data from evaluating the full 24hr. melatonin cycle. Melatonin Biorythym & Challenge (MBC) test _________________________________________________________

PRICE PER TEST IS: $175.00

1 Test.....$175.00

OSTEOPOROSIS-BONE HEALTH MARKERS-URINE

Bone Marker Test (Dpd)

THIS TEST WILL COVER THE FOLLOWING:

Dpd(BONE MARKER) URINE TEST

The Importance of Strong Bones

*During their lifetime, 1 in 3 women will break their hip bones. This is preventable. The health of your bones can be evaluated with a urine test. Empower yourself with information about your bones that will make a difference with intelligent choices. A case in point: A woman in her fifties showed significant bone loss on both an x-ray and the urine test. A postmenopausal salivary hormone test was given to her, she was found deficient in 3 hormones. Her doctor gave her a balanced hormone treatment. Nine months later her bone urine test became normal.

What is Bone Aging?

Bone turnover is a process that continues to take place throughout our lifetime. It is a delicate balance between bone formation and breakdown. In childhood and early adulthood, the process is strongly in favor of bone formation and this continues up to the age of 30-40 years; after which the balance starts to tilt to bone breakdown. This results in the gradual thinning of bone with age, or osteoporosis. Around the onset of menopause, bone turnover tilts in favor of bone breakdown. This is due to the persistant imbalance or decline in estrogen, progesterone, and other hormone levels.

How is it related to Menopause?

During cycling years most women have enough ovarian output of progesterone and estrogen. These two hormones promote bone growth. Around the mid-forties (usually 3-4 years before the cessation of menstruation) the levels of estrogen and progesterone start to gradually drop off, thus accelerating bone dissolution. In men, the drop of testosterone can lead to a similiar picture. Men convert testosterone into estrogen, therefore a decrease in testosterone can reduce estrogen levels.

Does it affect my Health?

Yes, it does. Bone aging leads to a disease called osteoporosis that results in bone thinning and, more importantly, bone fragility. Osteoporosis can affect you and your loved ones in several ways:

1.) Middle-aged and elderly people lose a few inches of their height due to osteoporosis.

2.) Many seniors are prone to hip fractures secondary to osteoporosis.

3.) 1.5 million bony fractures-at various body sites occur annually secondary to osteoporosis

Am I at risk for Osteoporosis?

Your risk for osteoporosis increases with:

-Age

-Sedentary life-style

-Non-black skin color

-Smoking

-Alcohol consumption

-Family history of osteoporosis

-Around the time of menopause ...

and when your doctor says that you have:

-Thyroid disease

-Diabetes

-Adrenal impairment

-Kidney disease

-Rheumatoid arthritis

If you are at a high risk for developing osteoporosis, your physician has different measures and options to objectively assess your risks, and these include:

-Bone density measurement: employs radioactive or x-ray sources to measure your bone strength and mineral content.

-Urine testing: employs one random urinary specimen to assess the rate of bone breakdown in your body.

What does your lab offer me?

We are offering you a urine test to assess for bone breakdown. The test is called Pyrilinks-D (Dpd). We can also measure your estrogen, progesterone, & four other hormone levels from a saliva specimen (separate test).

Urine Pyrilinks-D Result

What was Measured:

Your urine was tested for deoxypyridinoline (Dpd) by the Pyrilinks-D assay. Dpd is a specific urinary marker for bone resorption (loss). Your bone is in a constant dynamic state of building up and breaking down, and when the breaking down exceeds the building up, your bone thins and becomes porous, a condition known as osteopenia. If the thinning is not interrupted by intervention, you become susceptible to bone disease (osteoporosis) and, ultimately, serious fractures. If your Dpd level is higher than the acceptable range for healthy bone turnover, you should consult your healthcare practitioner.

Your Test Result

Your urine Pyrilinks-D test result consists of one page that contains your name, your healthcare provider’s name, both addresses and your Pyrilinks-D result, displayed and graphed.

Your Result and the Range

A Pyrilinks-D Value Greater than 6.5

A value higher than 6.5 indicates that your rate of bone loss is greater than that for healthy young men and women. You are losing bone faster than you are building it. In general, if this rate of bone loss continues, you could be more prone to disease. It is suggested that a visit to your healthcare provider is in order if the value is greater than 6.5 to discuss possible causes and solutions.

How to use this test:

Your doctor can use the Pyrilinks-D urine test to: screen for osteoporosis in conjunction with bone densitometry as a follow-up test to monitor the bone response in Hormone Replacement Therapy and/or osteoporosis treatment protocols

If you wish to monitor your Hormone Replacement Therapy through our office we use saliva home testing to test for the following::

salivary hormone measurement

-Estradiol

Estrone

Estriol

Progesterone

DHEA

Testosterone

LH

FSH

all from one salivary sample (Expanded PHP-1). This is a separate test.

Who Needs the Dpd Bone Marker?

To determine if the Dpd Bone Marker is appropriate for your health problems and concerns, consult with your physician.

Common Applications of this Panel: · Individuals over 40 years of age

· Women around menopause

· People with non-black skin color

· Non-active persons- people with sedentary life-styles

· Smokers

· People with a family history of osteoporosis

· Individuals who have diabetes,kidney disease,

adrenal impairment or rhuematoid arthritis.

PRICE PER DPD TEST IS: $95.00

This price includes test and Doctors consultation

1 Test.....$95.00

THE EXPANDED FEMALE HORMONE PANEL WITH DOCTORS CONSULTATION-THIS TEST IS FOR WOMEN STILL HAVING THEIR MENTSTRUAL CYCLE

The Female Hormone Panel.:

This test is for women who still have their menstrual cycle.

The ovaries are a very important part of the female reproductive organs. The ovaries are located on the right and left side of the pelvic cavity next to the uterus. Each weighs about 15 grams. The human female is born with immature ovaries which gradually mature until the start of menstruation signals a fully functional reproductive system.

The Cyclical Pacing of the Ovaries:

The human ovary releases its hormones in a cyclical manner which is referred to as the menstrual cycle. The average cycle is about 26-30 days. The timing and pacing of hormone release is governed by GnRH, FSH & LH, hormones from the hypothalamus and pituitary gland in the brain. The two major classes of ovarian hormones released during the menstrual cycle are Estrogens and Progesterone, which are known as female steroid sex hormones. The major and most active Estrogen released is Estradiol, while the major Progestin is Progesterone.

The female cycle has 3 physiologic phases (see Figure 1): The follicular phase starts with the onset of menstrual blood flow and is of variable length. This phase is normally characterized by both low Estrogen and Progesterone output. The ovulation phase is 1 to 3 days long and the human ovum (egg) is released in this phase. This phase is characterized by high estrogen levels.

The luteal phase is rather constant in length, 12-14 days, and ends with menses. Compared to the follicular phase, the luteal phase is characterized by high Progesterone concentrations and a moderate increase in Estrogens.

Functions of Female Sex Hormones:

Estradiol and Progesterone affect several target organs involved in a successful conception and pregnancy. Additionally, these hormones maintain a number of secondary sexual characteristics such as reduced bodyhair, soft skin texture, a higher voice pitch, possible release of certain pheromones, etc..

Target Organs of Estrogen & Progesterone.:

The Uterus:

Estradiol prepares the uterus for conception and produces a 3-5 fold increase in the thickness of its inner lining, and also promotes uterine gland development and mucus secretion. Progesterone causes a swelling of the uterine lining, an increase in glycogen (a complex sugar) content, and an increase in the mucus secreted by the uterus. If conception does not occur, the uterine lining is shed, resulting in the menstrual flow.

Fallopian Tubes:

Sex hormones stimulate the fallopian tubes to move the egg toward the uterus. The fallopian tubes also secrete nutritious fluids that nourish the egg, the sperm and ultimately the embryo when fertilization occurs.

Vagina:

Estrogens promote the thickening of the vaginal lining and increase its secretions, which makes the lining more resistant to infections.

Breasts:

Before puberty, the breasts grow only in proportion to the rest of the body, but under the influence of Estradiol and Progesterone during puberty, the breasts develop to maturity. During the menstrual cycle, excess Estradiol causes breast swelling and tenderness.

Bones:

In the adult female, Estradiol and Progesterone play an important role in the inhibition of osteoporosis and improve the incorporation of calcium and magnesium into bone. This is why doctors prescribe Estrogen for menopausal women.

Kidney:

Estrogens cause the body to retain sodium which results in fluid buildup. Conversely, Progesterone causes a loss of excess sodium and retained fluid. Before the period begins, there may be a relative excess of Estrogen over Progesterone which commonly leads to several of the PMS associated complaints.

Liver:

Estradiol has stimulatory effects on liver proteins which may reduce thyroid hormone availability and increases the risk for cardiovascular disease. Estradiol also slows the process of liver detoxification of various harmful substances.

Miscellaneous:

Estradiol can elevate blood sugar in certain susceptible individuals. Progesterone can increase the appetite and has a general calming effect on the nervous system, especially at night.

What We Test For:

The Female Hormone Panel is a simple, non-invasive test. Eleven saliva samples are collected during specified time periods throughout the menstrual cycle.

The FHP, for the first time in routine medical practice, will allow both patient and doctor to actually view the profile of Estrogen and Progesterone simultaneously (See Figure 1). Diagnostic guesswork is minimized, and hormonal balance evaluation and customized treatment becomes a reality with the FHP.™

In addition, we report the cycle average for Testosterone and DHEA.

The expanded eFHP™ also includes five FSH & LH measurements to see if brain control and stimulation of the ovaries is optimal.

Applications of the Female Hormone Panel:

Detection of Luteal Phase Defect:

There are at least three luteal phase defect patterns which are characterized by a reduced output of Progesterone that leads to Estrogen dominance. This imbalance is usually associated with PMS, infertility, fibroids and other female hormonal problems and can be readily detected by our panels.

Hormonal Imbalance and PMS:

Many women suffer from hormonal imbalance in the Estrogen to Progesterone ratio. Our panels can objectively evaluate the hormonal state with great accuracy which, in turn, provides specific insights for appropriate intervention or treatment to relieve hormonal imbalance and PMS related symptoms.

Customized Hormone Therapy:

Presently, female hormone therapy is not individualized to the needs of each woman because current diagnostic tests do not provide sufficient data. Consequently, most women are empirically treated without regard to their individualized physiology and specific needs. The FHP,™ for the first time, will allow a clinician to customize therapy to each female patient.

Other Applications:

The FHP™ can also be used to detect & monitor the following:

Functional infertility Influence of lifestyle (diet, exercise, etc.) on the cycle

Menstrual problems originating in the brain

Early pregnancy problems - spontaneous miscarriage

Cycle irregularities, following the use of birth control pills

Dysmenorrhea, i.e. painful and heavy periods

Migraine headaches

Endometriosis and cystic ovarian disease

Early Osteoporosis

Advantages of the Female Hormone Panel:

Convenience: requires no blood draws, therefore no repeated clinic visits and avoids the inconvenience of the 24 hour urine collection.

Economy: the fee for the 11 sample test is less than that of 2 blood determinations or a urine analysis for Estrogen and Progesterone.

Physiological Accuracy: research has demonstrated that the free hormone fraction predominates in saliva. Hormones can be found free or bound to protein. The free hormone fraction is very important to ascertain because it is the bioactive fraction that most significantly influences living cells. The salivary female hormone levels correlate at 93% with the free hormones in the tissues. One or two blood determinations or a 24 hour analysis of urine for these hormones cannot give an idea of the ovaries' hormonal productivity. The FHP™ gives a good approximation of the ovarian capacity over a whole cycle.

Do you need the FHP™?

To determine if the FHP™ is the appropriate test for your female related problems, call our office at 800-333-9942. We will be happy to assist you.

1 AT-HOME KIT.....$275.00

THE EXPANDED GASTROINTESTINAL HEALTH PANEL WITH DOCTORS CONSULTATION

The Expanded Gastrointestinal Health Panel.

The gastrointestinal tract is essentially an external part of the body. This is the reason we do not have to sterilize our food, but only be sure it is clean and wholesome. Presently, the risk of being infected or infested by pathogenic organisms through food and water is ever increasing. This is due to several reasons:

immigration; frequent overseas travel; importation of vegetables and fruits; lack of a public health policy to screen food handlers for transmissible pathogens; outdoor and wilderness excursions; alternate life- styles; agricultural pollution; pets at home, etc.

Currently, World Health Organization studies indicate that about 1/2 billion individuals are infected annually by Amoeba histolytica and about the same number are infected by Giardia and cryptosporidium. Considering all parasites, more than 1/4 of the Earth's population is infected at any one time. More serious efforts must be made to prevent, identify, and treat these widespread and debilitating infections.

Mode of transmission & who is at risk:

The predominant method of transmission of parasites is the fecal-oral route through hand contact with infected individuals or via contaminated water and food. Many parasites are highly transmissible within a household environment. All family members should be tested if one member is positive for GI infection.

People with suppressed immunity, eg. T-cell (white cell) dysfunction and defects in intestinal antibody (IgA) secretion, are predisposed to protracted and heavy infections with GI pathogens. Individuals with cancer and those receiving chemotherapy for cancer are very susceptible to parasitic infection(s).

Frequent and excessive overutilization of antibiotics renders the GI tract more susceptible to chronic overgrowth of harmful micro-organisms. These can produce a wide range of systemic toxins and/or cause severe irritation of large areas of fragile, nutrient absorbing intestinal tissue.

Bodily functions affected by GI pathogens:

Intestinal pathogen infections cannot be clinically differentiated solely on the basis of medical history, physical exam and/or symptoms. Specific diagnosis requires laboratory evaluation and conformation. In most laboratories the general request for stool ova and parasite screening does not include the specialized testing and confirmation provided by the GI Health Panel.™ Asymptomatic, mild symptomatic and overt GI pathogen infections can affect and deter gastrointestinal function, and, if undetected, will lead to chronic illness.

Treatment & Prevention:

Detection and specific diagnosis of the pathogens, including a broad spectrum of microflora and common parasites is of paramount importance. This is because successful therapy is dependent on two primary issues:

First, accurate and specific diagnosis of causative agent in a patient who presents with otherwise general and non-speci?c complaints and symptoms.

Second, specific therapeutic agents can be targeted to eradicate offending micro-organisms with an extremely high success rate, with minimal side effects.

Prevention notes:

Observe strict personal hygiene habits

Eat cooked food, when outside your home Wash fresh fruits & vegetables with soap & water Avoid drinking potentially contaminated surface water

Before overseas travel, contact the CDC for tips

Restrict pets to designated parts of the home

Wash hands after touching pets

Gastrointestinal Health Panel™

The GI Health Panel™ is a non-invasive screen of the gastro-intestinal tract and its function. It includes at least 15-22 individual, but related tests. Stool and saliva samples are submitted by the patient after home collection.

Logic of testing:

To insure high sensitivity and specificity of pathogenic organism detection, these tests utilize proven biochemical and state of the art immunological and other methods. The panel includes:

Pathogen screening:

Stool cultures for yeast

Bacterial stool pathogens

Clostridium difficile Antigens

Giardia Antigen

Cryptosporidium Antigen

Ameba histolyica Ab

Tapeworm Ab

Roundworm Ab

Tissue Worm Ab

Toxoplasma Ab

H. pylori Ab

Ova and various parasites.

Digestion related screens:

Enzyme levels and immunochemical markers for intolerance to common offending foods.

Intestinal function markers to evaluate irritation and inflammation; markers indicate overall status of gut immunity and integrity, i.e. occult blood, etc.

We also test for:

Chymotrypsin

Occult blood

Fecal pH

Total intestinal SIgA

Intestinal Lysozyme

Alpha-Anti-Chymotrypsin

Gluten Intolerance Test

Cow's milk intolerance

Soy intolerance

Egg intolerance

The GI Health Panel™ strikes a balance between comprehensive screening and economy by bundling appropriate individual tests that would otherwise cost over $700 at current prices. All the tests are insurer reimbursed with the appropriate provider documentation.

Advantages & Benefits:

Non-invasive sampling: saliva and stool

Home collection: no office visit Economical and insurance reimbursable

Comprehensive:

detects a broad spectrum of common pathogens and includes digestion efficiency evaluation

Improved wellness: general GI complaints identified and resolved

Modular: retesting of one or several abnormal findings is available without repeating the entire panel.

Common applications of this panel:

Individuals with chronic and vague GI symptoms including:

Frequent bloating, gas, cramping, and constipation Frequent travel within US and/or overseas

Frequent eating outside the home

Food handlers - to protect others

Food preparers at restaurants, homes, schools, etc.

Institutionalized individuals

Uniformed services

Dormitory Residents - common quarters

Children that go to daycare centers

Who needs the GI Health Panel™?

To determine if the GI Panel™ is appropriate for your gastro-intestinal and other health problems, call our office at 800-333-9942 with any questions.

1-AT-HOME KIT.....$285.00

THE EXPANDED POST MENOPAUSAL FEMALE HORMONE PANEL WITH DOCTORS CONSULTATION-THIS TEST IS FOR WOMEN NOT HAVING THEIR CYCLE FOR AT LEAST SIX MONTHS

The Post-Menopausal Hormonal Panel™

Literally, menopause means the cessation of the monthly menstrual cycle for six missed periods or more and signals the end of a woman's natural childbearing years. Menopause is neither a disease nor an illness, it is a natural and usually gradual change in glandular function. It has its origins in the beginning of menses and culminates in a series of hormonal changes that result in the cessation of menstrual flow. This transition produces a variety of bodily manifestations and symptoms, and is due to changes in production of hormones and the timing of their release.

Various body parts undergo change and can produce one or more of the following symptoms:

Endocrine:

Bleeding irregularities

Vaginal dryness

Hot flashes / sweats

Changes in sex drive

Nervous system

Insomnia

Nervousness, irritability

Headache

Mood Changes

Depression

Metabolic changes

Skin aging / cosmetic changes

Osteoporosis

Altered fat and carbohydrate metabolism

Atherosclerosis

What can you do about it?

Here are your options:

There are several therapeutic options which may minimize or even eliminate many of the symptoms:

Treat symptoms using synthetic hormones without hormone level testing.

Treat symptoms using natural hormones without any testing.

Treat and correct symptoms using natural hormones with testing for hormone levels before & after treatment.

Why should you test?

Hormones are powerful substances that control multiple functions throughout the body. Hormone levels should be sufficient and balanced. Too much or too little of them is not conducive to long-term emotional, mental and bodily health.

By not measuring the hormones before and after treatment your hormone picture is, at best, an educated guess, since hormone levels from woman to woman can vary 200 - 1,500%. In fact, many women need only one hormone, while others require 3 or 4 different kinds.

Just as you cannot balance your bank account without numbers on your bank statements, hormone testing provides both a basis for treatment and proximity to your goal.

One can then: Customize natural hormone dosing to meet individual needs. Optimize hormone levels for minimum dose to relieve symptoms. Avoid overdosing.

Achieve appropriate and compatible physiologic levels of several hormones.

Increase sense of "well being" by removing underlying hormone deficit and imbalances. What do we test for in the Post menapausal profile: and what does it tell you?

The test utilizes your saliva as a sample for measuring hormones:

Testosterone

DHEA

Progesterone

Estriol

Estrone

Estradiol

FSH

LH

Saliva hormone values reflect the tissue concentration of your hormones or FREE HORMONES. These are the active hormones in your body.

Blood and urine contain only the total combined hormone picture and not the free active hormone results. Active fraction measurements are superior to blood and urine measurements both in diagnosis and treatment.

How can we help you?

Let us take a common example:

A woman suffers from several symptoms-migraines, hot flashes and emotional fragility. Her doctor treats her with natural estrogens, but he does not do any testing to determine quantities or types of hormones that will meet her specific needs. The symptoms are under control, but her risks are the following: Increased blood pressure

Endometrial cancer (uterine cancer) Fibroid growth Gallbladder disease Over 15 years, at least twice the risk of breast cancer

What could we have found out if we had tested her saliva hormone levels? We would have known that she has too much estrogen, not enough progesterone to balance the estrogen, low DHEA, and marginal testosterone.

But, she felt good on the estrogen, many will say. Yes, however, the silent killers (cancer, blood pressure, heart disease) rarely make anyone feel bad at the start. Her best course is a new treatment plan, designed around the objective saliva hormone measurements.

Ask OUR OFFICE for the Expanded PHP-1™ Panel to measure your hormones.

How do you benefit?

There are five distinct areas that you will benefit from using the saliva tests.

They are affordable and less expensive than blood or urine tests. Blood testing for 8 hormones costs $250-$300 more than saliva testing.

Collection procedure spares you the pain of venipunctures with a needle.

Results are more clinically reflective of your hormone status and needs.

Results can lead to an individualized and customized treatment plan using natural hormones.

You will minimize overdosing and underdosing. This will insure that you use only the proper hormones in the appropriate amounts.

With salivary hormone testing, guesswork is past news.

All fees include doctor/patient consultation with test results.

.....$145.00

THE MALE EXPANDED HORMONE PANEL WITH DOCTOR CONSULTATION

Traditionally, age-related male hormone changes were not considered problematic because fertility in men persists until an advanced age. In contrast, women undergo ovarian function failure and require multiple hormone replacements. More careful evaluation in males shows progressive age-related changes including: Decreased muscle mass & strength Decreased vigor, low energy Decreased libido Insomnia Nervousness & Depression Hair loss These changes usually begin in the fourth and fifth decades and point towards hormone imbalances and defciencies which may be considered the male equivalent of menopause, i.e. the Andropause.

What you can do about male hormone imbalance Optimal health is dependent on the balance of hormones, and not just a single hormone. Currently, men with low androgen hormones can beneft from hormone replacement therapy. Also, men with imbalances in their androgen to estrogen and progesterone can also be hormone supplemented to achieve balance.

Supplemental hormones can be given by mouth, by injection, by skin patch, or by implant. Androgen supplementation, in states of deficit, improves alertness and produces a feeling of well being, with a reduction in abdominal fat and enhanced lean body mass.

Testosterone production in males is mainly a testicular function. Pituitary sex hormones (FSH & LH) stimulate and regulate this function. Specifcally, LH (Luteinizing hormone) stimulates testosterone production in the testicles. This process is under negative feedback, meaning that testosterone levels regulate LH secretion. FSH (Follicle Stimulating Hormone) and testosterone stimulate sperm production.

Why measure male hormones?

Measurements of hormones can be used in two general ways:

To estimate the body's own production-baseline test To measure levels of hormones after supplementation-therapeutic monitoring Baseline measurements will show normal and abnormal levels of six distinct hormones. If levels are too low, too high or hormone ratios are outside of expected limits, an objective treatment plan can be developed for the individual. Symptoms are not a substitute for measuring hormone levels because many symptoms may involve non-hormonal factors.

Using appropriate tests for monitoring hormone therapy is crucial in establishing the appropriate dosing regimen. This reduces the chance of undesirable side-effects and maximizes benefcial effects. For example, excessive use of androgens (testosterone, androstenedione, DHEA and testosterone derivatives) can activate subclinical prostatic tumors which are androgen-dependent. Monitoring is especially important in older males. By the age of 70, at least 50% of men have subclinical prostate cancer. These are especially susceptible to growth stimulation by androgens.

The roles of the six hormones we test are highlighted below:

DHEA - Is the precursor for both male and female hormones. Also, it is an anti- stress hormone produced by the adrenal glands. Unmonitored intake can easily alter the delicate balance between male to female hormones.

Androstenedione - Is a weak male hormone (androgen) and a precursor of both male & female hormones. Unmonitored intake in men can cause excessive female hormone production with minimal male hormone production. In women, unmonitored intake usually causes excess male hormone production with body & facial hair stimulation.

Testosterone - Is the main testicular androgen and is a precursor to the highly potent dihydrotestosterone male hormone. Excessive amounts of testosterone promote hardening of the blood vessels, aggression, prostate problems and increase in total cholesterol.

Dihydrotestosterone (DHT) - Is made from testosterone in certain tissues. The rate of its production is controlled by the level of free active progesterone. Excess DHT causes prostate enlargement and thinning of scalp hair.

Progesterone - This hormone is important in both sexes. It is a natural calming agent to our nervous system. It also keeps in check excessive DHT production and counterbalances the effects of excessive estrone. Unmonitored intake can lead to breast enlargement, depression and weight gain.

Estrone - Is an estrogen that both sexes produce in the fat cells. The more fat, the more estrone which in turn itself promotes fat deposits. It is produced from androstenedione and excess of estrone can cause breast enlargement and contributes to prostate enlargement. In males, a certain low level of estrone is mandatory to balance the androgens.

What we test & what it tells you:

Using your saliva sample, the regular MHP™ panel measures six hormones:

DHEA

Androstenedione

Testosterone

Dihydrotestosterone

Estrone

Progesterone.

The eMHP™ panel measures these six hormones plus FSH & LH.

The hormone levels in saliva refect the active tissue concentrations, while blood contains mostly protein bound hormones, whose active levels can only be estimates at best. Urine contains both the active hormones and numerous metabolites and can only be used to gain gross estimate of hormone production over time. Active fraction measurements from saliva are superior to blood and urine total hormone levels in diagnosis and treatment.

This test is for you if you are...

Middle aged and having:

impaired libido

erectile dysfunction

baldness and/or extremity hair thinning

fat accumulation around the waist

urinary symptoms: pain and/or frequency; urgency;

interrupted stream

change in sleeping habits

lack of enthusiasm for life

increase in bad cholesterol, decrease in good cholesterol

your Dr. tells you that you have osteoporosis

Young and having:

impaired libido

erectile dysfunction

early baldness

inability to lose weight

How do you benefit?

There are five distinct areas that you will benefit from using the saliva tests:

They are affordable and less expensive than blood or urine tests. You save $250 - $300 on six hormones.

Collection procedure spares you the biohazards and pain of venipunctures.

Results are more clinically refective of your hormone status and needs.

Results can lead to an individualized and customized treatment plan using natural hormones.

You will minimize overdosing and underdosing. This will ensure that you use only the proper hormones in the appropriate amounts.

With salivary hormone testing, guesswork is minimized.

Total fees include doctor-patient consultation.

.....$150.00

THE NEW ADRENAL STRESS INDEX TEST WITH DOCTOR'S CONSULTATION

The NEW Adrenal Stress Index™ TEST WITH DOCTORS CONSULTATION

WHY YOU SHOULD CONSIDER TAKING THE NEW ADRENAL STRESS INDEX TEST:

Common Adrenal Related Symptoms.:

HERE IS A LIST OF POSSIBLE SYMPTOMS IF YOU HAVE INADEQUATE OR LOW ADRENAL FUNCTION

Weight Loss / Anorexia

Progressive Fatigue / Lethargy

Hypoglycemia

Diffuse Muscle & Joint Pains

Hypercalcemia

Low Serum Sodium / Salt Cravings

Skin Hyperpigmentation

High Serum Potassium

Anemia / Lymphocytosis

Lightheadedness upon standing

Abdominal Pain / Diarrhea.

If your Adrenals are overactive you may have the following sypmtoms.:

Weight gain / Truncal Obesity

Emotional Lability / Depression

Glucose Intolerance Insulin Resistance

Osteopenia / Fractures

Hypertension / Sodium Retention

Thin hyperpigmented skin / Striae

Sleep Disturbance

Poor Concentration / Memory Loss

Menstrual Dysfunction / Impotence

Increased Blood Lipids.

BRIEF DESCRIPTION OF ADRENAL GLAND FUNCTION.:

The adrenals are two small glands, each weighing 3 to 5 grams, that are located above the kidneys. The adrenals have one of the highest rates of blood flow per gram of tissue, and the highest content of Vitamin C per gram of any tissue in the body.

Each adrenal gland is composed of two separate functional entities. The outer zone, or cortex, accounts for 80% to 90% of the gland, and secretes adrenal steroids (Cortisol, DHEA(S) and Aldosterone). The inner zone, or medulla, comprises 10% to 20% of the gland, and secretes the catecholamines adrenaline and nor-adrenaline. Cortisol, DHEA and adrenaline are the three main adrenal stress hormones.

The Adrenal Rhythm & Its Importance:

The human adrenal gland does not secrete its steroid hormones at a constant level throughout the day. The hormones are actually released in a cycle with the highest value in the morning and the lowest value at night. This 24-hour cycle is called the circadian rhythm. An abnormal adrenal rhythm can influence many functions of the body, some of which are listed below.

1. Energy production: Abnormal adrenal function can alter the ability of cells to produce energy for activities of daily living. People who have a hard time rising in the morning, or who suffer with a low energy level during the day, often have abnormal adrenal rhythms and poor blood sugar regulation.

The maintenance of a stable blood sugar level depends on food choice, lifestyle, adrenal function and insulin activity. This panel measures stress hormones and insulin, to help ferret out causes of fatigue, cravings and obesity.

2. Muscle & joint function: Abnormal adrenal rhythms are known to compromise tissue healing. Reduced tissue repair and increased tissue breakdown can lead to muscle and joint breakdown with chronic pain.

3. Bone health:

The adrenal rhythm determines how well we build bone. If the night cortisol level is elevated and the morning level is too high, our bones do not rebuild well, and we are more prone to the osteoporotic process. Stress is the enemy of the bones. In postmenopausal women, the effect of stress worsens due to the female hormone imbalances.

4. Immune health: Various immune cells (white blood cells) cycle in and out of the spleen and bone marrow for special conditioning, and possible nourishment and instructions. This immune system trafficking follows the cortisol cycle. So, if the cycle is disrupted, especially at night, then the immune system is adversely affected. Short and long-term stress is known to suppress the immune response on the surfaces of our body as in lungs, throat, urinary and intestinal tract. With the reduction in the surface antibody (called secretory IgA), the resistance to infection is reduced and allergic reactions are believed to increase.

5. Sleep quality:

The ability to enter REM sleep cycles, i.e. regenerative sleep, is interrupted by high cortisol values at night and in the morning. Chronic lack of REM sleep can reduce the mental vitality and vigor of a person and induce depression.

6. Skin regeneration: Human skin regenerates mostly during the night. With higher night cortisol values, less skin regeneration takes place. So, a normal cortisol rhythm is essential for optimal skin health (See Figure 2).

7. Thyroid function: The level of Cortisol at the cell level controls thyroid hormone production. Quite often, hypothyroid symptoms such as fatigue and low body temperature are due to an adrenal maladaptation.

8. Grain intolerance & stress: About 12-18% of the U.S. population suffers from a genetic intolerance to grain. Specifically, a high incidence occurs in Celtic, Germanic, and Nordic derivation. The gut becomes inflamed within 30 minutes after consuming the grains and this can lead to an adrenal stress response, increased cortisol and reduced DHEA.

THE TEST DESCRIPTION:

The Adrenal Stress Index TEST™ (ASI™)

Four saliva samples are taken by you,at home at specified times.

1. 4 x Cortisol: Helps evaluate stress response 2. DHEA: Helps determine stress adaptation

3. 17-Hydroxyprogesterone

4. 2 insulin tests

5. Total Salivary SIga

6. Gliadin antibodies

Your health care provider can use the findings in this panel to recommend customized treatment and preventive measures that may include diet and lifestyle changes, hormones, botanicals and vitamins.

Advantages of the ASI™ The test is non-invasive & can be performed wherever you are.

Saliva is collected under real life conditions. There are no stressful blood draws and no gallon sized urine containers to carry around for 24 hours.

With blood and urine testing, a number of borderline adrenal conditions are missed due to lack of sensitivity. This is not the case with the ASI™ because samples are taken within one circadian cycle and the more definitive "FREE" fraction is measured. The ASI™ is an in-depth test, such that options for treatment are expanded by 400-500% over serum and urine test results.

Abnormal adrenal rhythm can influence:

Energy Production

Bone Health

Immune System Health

Sleep Quality

Skin Regeneration

Thyroid Function

Muscle and Joint Function

Do you need the ASI™ Test?

To determine if the ASI™ is the appropriate test for assessing your health condition, ask Dr. Guberman for a Metabolic Stress questionnaire. The score can help determine a course of action.

The ASI™ is mostly ordered for individuals that suffer from:

Chronic stress and related health problems

Lack of vitality and energy

Muscle and joint pain

Hypoglycemia and insulin resistance

Migraine headaches

Osteoporosis

Sleep disturbances Poor memory

Alcohol intolerance

Stress maladaptation Low sex drive

Low body temperature

The Adrenal Stress Index Test is well worth consideration.

The adrenal test kit is sent to you. You follow directions within the box supplied and, when finished, you mail the kit box directly to the lab. Dr. Guberman receives the results usually with in two weeks and a consultaion time is reserved for you to have the results explained as well as a course of action plan determined.

The fees for testing includes doctor-pateint consultatiion and all testings.

one test kit.....$149.00

THE THYROID PANEL

THIS SALIVA PANEL OF TESTS INCLUDE:

FREE T4

FREE T3

THYROID STIMULATING HORMONE

THYROID ANTIBODY

SCIENTIFIC ADVANTAGES:

MEASURING THE FREE FRACTION LEVEL IN TISSUE FLUID (SALIVA) GIVES A GOOD REFLECTION OF THE TISSUE DELIVERY OF THE HORMONE. THESE TESTS ARE SEVERAL TIMES MORE ANALYTICALLY SENSITIVE THAN THE BLOOD/SERUM TESTS THAT ARE USUALLY DONE

one test kit.....$155.00